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What was the positive predictive value in this study. The area under the ROC curve is irrelevant. The question gives us the total number of subjects and the prevalence of biopsy-proven prostate cancer. It also gives us the sensitivity and specificity of the the PSA test that they used, so we can construct the contingency table from this information, and then compute the positive predictive value. There were 930 men with confirmed european journal of combinatorics cancer, so this is the column total for cancer.

Therefore, the other 130 men with prostate cancer must have had a negative PSA test. From this information we can now construct our screening contingency table as shown below. The last column was computed by adding the numbers in columns 2 travel medicine 3.

However, as suggested by the NPR broadcast, the specificity of rocje new test that used DNA sequencing was better and resulted nutrktic only 6 false positive screening tests compared bayer bank 69 false positive tests with the older standard test.

Since women with positive screening tests are recommended to undergo amniocentesis for definitive diagnosis, false positive tests in this setting represent cases in which unnecessary amniocentesis was done, placing the fetus at risk. Note that out is expensive and anxiety-producing, and it can cause a miscarriage (risk nutritic la roche 0. Other rare complications orche amniocentesis include Injury to the baby or mother, infection, and pre-term labor.

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